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Central Service - Issue 6/2010

Central Service - Issue 6/2010

Central Service - Issue 6/2010


  • What's New in Standardization: Revision: Chemical Indicators
  • Bochum Hygiene and Sterilisation Meeting Celebrates its 100th Meeting
  • Klaus Böer - Initiator and Driving Force/Erratum
  • 11th Schleswig-Holstein CSSD Hygiene Forum, Damp, 31 October 2010
  • ASP Sterrad NX Technology Approved by AFSSAPS for Total Inactivation of Prions
  • Informations for Authors
  • Medical Device Reprocessing as Reflected 17 Years after Introduction of the Medical Devices Act. Evaluation of the DGSV congress workshop devoted to this topic


H. Biering, W. Fuchs, J. Staffeldt:
Analysis of Stainless Steel and Anodized Aluminium Material Compatibility with Foam Sprays Used for Keeping Used Surgical Instruments Moist

The material compatibility of four ready-to-use enzymatic foam cleaners on anodized aluminium and stainless steel was studied. This type of cleaner is applied in operating theatres to prevent bio-burden from drying on used surgical instruments. Cleaners were applied for one exposure time to test materials alone and in combination with blood. The study shows no or slight changes on the tested materials when contacted with most of the cleaners. Pitting corrosion was detected with one cleaner at extended contact time. This effect could be caused by the high chloride content in the product.


F. Rochefort:
The Role of Detergents in Prevention of Transmission of Creutzfeldt-Jakob Disease

To prevent transmission of Creutzfeldt-Jakob disease, studies have been carried out to investigate products or processes that would be at least as effective and easier to use than the reference products, i. e. sodium hypochlorite with 2 % activated chlorine and sodium hydroxide. This highlights the problem faced by Central Sterilisation Supply Departments (CSSDs) in finding a detergent endowed with effective cleaning properties and, accordingly, with a very low residual protein load. Different methods have been described in the literature for determination of the residual protein level but it is difficult to apply such methods in the CSSD. Conductance of medical device reprocessing at a central location means that there is an interval between the time the surgical instruments are used and the time they are reprocessed, which is conducive to protein fixation and confirms the need for "without delay" predisinfection (pre-soak) as practised in French hospitals.
The studies published are based on in vitro tests, showing that the products are able to modify prion protein and make it sensitive to the action of proteinase K, as well as on in vivo tests using steel wires that are used to simulate instruments and implanted into an animal model after having been exposed to the detergent. These studies do not permit comparison of their respective findings and they are in some cases contradictory, because they have been conducted under different conditions (strain, animal, dose, observation period, substrate used, etc.). The detergents tested were either products that are known in the laboratory setting, but have not been designed for routine use, proteases or detergents such as sodium dodecyl sulphate (SDS), or commercially available detergents. Published studies have attested to the efficacy of the following detergents: HAMO 100®, SEPTOCLEAN®, DECONEX 28 ALKAONE®, PRIONZYME®. However, as per the current provisions of Circular 138, the CSSD management cannot dispense with the use of sodium hydroxide.


L. Müller:
Monitoring Sterilization Processes - Value of Process Challenge Devices According to EN 867-5


P. Heeg:


Recommendations by the Quality Task Group (AK »Qualität«) Problems today - tomorrow, how can we solve them?!

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